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CD95 ANTIGENS
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DeCS
Descriptor
English
:
Antigens, CD95
Descriptor
Spanish
:
Antígenos CD95
Descriptor
Portuguese
:
Antígenos CD95
Synonyms
English
:
CD95 Antigen
Fas Cell Surface Death Receptor
TNFRSF6 Receptor
fas Antigen
fas Receptor
APO 1 Antigen
Receptor, TNFRSF6
Receptor, fas
fas Antigens
APO-1 Antigen
CD95 Antigens
fas Receptors
Receptors, fas
Tumor Necrosis Factor Receptor Superfamily, Member 6
Tree Number:
D12.776.543.750.690.500
D12.776.543.750.705.852.760.195
D23.050.301.264.035.195
D23.101.100.110.195
Definition
English
:
A tumor
necrosis
factor receptor subtype found in a variety of
tissues
and on activated
LYMPHOCYTES
. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and
APOPTOSIS
. Multiple isoforms of the protein exist due to multiple
ALTERNATIVE SPLICING
. The activated receptor signals via a conserved
death domain
that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the
CYTOPLASM
.
Mutations
in the CD95 gene are associated with cases of
autoimmune lymphoproliferative syndrome.
See Related
English
:
Autoimmune Lymphoproliferative Syndrome
History Note
English
:
1996; use ANTIGENS, CD95 (NM) 1989-1995; for FAS RECEPTOR use ANTIGENS, CD95 1998-1999
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
32837
Unique Identifier:
D019014
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS